A new version of AMDLSS5, an unofficial mod that runs Nvidia's DLSS 5 neural rendering on AMD's RX 9000-series cards, claims a 64% frame rate gain over other mods in Resident Evil Requiem.
The mod's creator said version 2.0 also runs 11% faster than the previous release of AMDLSS5. Both figures are the creator's own, and the 64% comparison covers one game against unnamed "other mods", so treat it as a pointer rather than a benchmark.
The starting point matters. A different DLSS 5 mod tested on a Radeon RX 9070 XT managed nine frames per second in Cyberpunk 2077 at 4K with ray tracing on Ultra and FSR 4 set to Balanced. A 64% gain on a number that low would still leave the game short of playable, though the two tests use different games and settings and cannot be compared directly.
Part of the problem is DLSS 5 itself. In NBA 2K27, an RTX 5080 lost up to 73% of its frame rate at 4K with the feature on, with sizable drops at lower resolutions too. If Nvidia's own hardware pays that price, a port to another vendor's cards was never going to be free.
The creator's list of supported games is long: Cyberpunk 2077, The Witcher 3 (DirectX 12 version only), Red Dead Redemption 2, Final Fantasy XVI, Monster Hunter Wilds, Grand Theft Auto V Enhanced (offline story mode) and others. Several entries require picking FSR 2 or XeSS as the in-game upscaler, which suggests the mod hooks into those slots. Installation is a downloaded installer that adds, updates or removes the mod in one click.
Some Reddit commenters said image quality is poor with the mod on, a fair warning for anything unofficial.
The larger question is whether DLSS 5 can ever be cheap enough to matter on any card. A mod that speeds it up on Radeon hardware is useful only if the starting point was a feature people want to run at a real frame rate.